The Tyler Medical Clinic
Assisted Conception - Affordable Infertility Treatments
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The Tyler Medical Clinic Assisted Conception - Affordable Infertility Treatments
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Addison Disease A consequence of long-term under function of the outer portion of the adrenal gland. In medical terms, chronic insufficiency of the adrenal cortex. This may be due to a number of different insults to the adrenal gland including physical trauma, hemorrhage, tuberculosis, and destruction of the cells in the pituitary gland that secrete ACTH (adrenocorticotropic hormone) which normally drives the adrenal. Addison's disease is characterized by bronzing of the skin, anemia, weakness, and low blood pressure. The U.S. President John F. Kennedy is said to have had Addison disease. The adrenal cortex insufficiency was named after the British physician Thomas Addison (1793-1860). When Addison identified adrenal insufficiency in 1849, tuberculosis (TB) was responsible for 70-90% of cases. As the treatment for TB improved, the incidence of adrenal insufficiency due to TB of the adrenal gland greatly decreased in developed countries. TB now accounts for around 20% of cases of primary adrenal insufficiency.
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